{"id":"loong-wang","hidden":false,"ipfs":"QmX94MqoaVwQvC9gYLxbQsDpdiTbeWYzUYLh3aDDSosRSD","language":"en","transactionHash":"0x0985a28add2e285b83511450ac34fee2a171ac7dc0fe0f99ef07e1d37b343793","created":"2023-11-17T13:39:47.000Z","updated":"2024-01-08T17:08:55.549Z","title":"Loong Wang","summary":"Loong Wang is a computer scientist and entrepreneur who co-founded Ren, QDX, Automera, and Alta, a financial-infrastructure company formerly known as Metal.","content":"**Loong Wang** is a computer scientist and entrepreneur. He co-founded [Ren Protocol](https://iq.wiki/wiki/ren-protocol) and served as its Chief Technology Officer (CTO) until January 2021, alongside [Taiyang Zhang](https://iq.wiki/wiki/taiyang-zhang) as CEO.[[1]](#cite-id-2em9wbmpceh)[[5]](#cite-id-m0cixe4jtqn) He later co-founded biotechnology ventures including Talo Labs, QDX, and Automera, and is the co-founder and CEO of Metal, which rebranded as [Alta](https://iq.wiki/wiki/alta) in November 2026.[[1]](#cite-id-2em9wbmpceh)[[12]](#cite-id-7zt0ogz27i)[[13]](#cite-id-eyab218rys)\n \n\n [YOUTUBE@VID](dC52MY0CqWs)\n\n \n\n## Education\n\nLoong Wang attended the Australian National University (ANU) where he graduated in 2016 with a Computer Science degree in Advanced Research and Development (Honours).[[1]](#cite-id-2em9wbmpceh) \n \n\n## Career\n\nWang began as an academic tutor at the Australian National University (ANU) in 2014 and later served as a researcher there from 2015 to 2016. He also worked as a software developer at Neucode, a software development agency, from 2015 to 2017.[\\[1\\]](#cite-id-2em9wbmpceh)​\n\n### Metal (now Alta)\n\nWang introduced Metal on June 25, 2026, with co-founders [Catherine Porter](https://iq.wiki/wiki/catherine-porter) and Jack Zhang. The company is developing blockchain-based financial infrastructure for regulated institutions and tokenized finance, with planned privacy, programmable compliance, identity, and authorization features, including support for agent transactions. Airwallex became its design partner, connecting local payment networks across 200 countries and 90 currencies.[\\[14\\]](#cite-id-0zke973eme)​[\\[13\\]](#cite-id-eyab218rys)​\n\nOn November 10, 2026, the company announced that it had rebranded as [Alta](https://iq.wiki/wiki/alta) and raised a $47.5 million Series A led by Index Ventures, bringing disclosed seed and Series A funding to $80 million. Wang is [Alta](https://iq.wiki/wiki/alta)’s co-founder and CEO. Alta described a planned liquidity-management product and infrastructure for institutional [blockchain](https://iq.wiki/wiki/blockchain) finance; Airwallex chose to build on the system.[\\[13\\]](#cite-id-eyab218rys)​\n\n### Ren Protocol\n\nIn 2017, he co-founded [Ren](https://iq.wiki/wiki/ren-protocol) (formerly known as Republic Protocol) alongside [Taiyang Zhang](https://iq.wiki/wiki/taiyang-zhang) and worked there as a CTO. Wang’s profile lists his Ren CTO tenure as ending in January 2021; his role was later described as advisory. Ren is an open protocol that facilitates the permissionless and private transfer of value between any [blockchain](https://iq.wiki/wiki/blockchain).[\\[5\\]](#cite-id-m0cixe4jtqn) Ren's core product, [RenVM](https://iq.wiki/wiki/renvm), brings interoperability to [DeFi](https://iq.wiki/wiki/defi) through a decentralized custody solution that allows the movement of assets between [blockchains](https://iq.wiki/wiki/blockchain).[\\[6\\]](#cite-id-lwwi1i6fch)​[\\[1\\]](#cite-id-2em9wbmpceh)​[\\[10\\]](#cite-id-00rgf0pl5nzpi)​\n\nWang was introduced into the [blockchain](https://iq.wiki/wiki/blockchain) space when he was asked by [Zhang](https://iq.wiki/wiki/taiyang-zhang) to work together on [Ren](https://iq.wiki/wiki/ren-protocol).[\\[7\\]](#cite-id-3nz4vlfc4tr)​\n\n> \"I did a lot of research at Australia National University around decentralized systems. I collaborated with Cray, a supercomputing company, and helped them with their supercomputing language Chapel and then I went on to do my honors thesis in the same area and built my own language which specialized in systems.\n> I'd worked together with Tai. for several years and so when he came to me with the idea of working in blockchain and decentralized space there was no way I was gonna turn that down\" - Wang recalls his journey into blockchain & Ren in an interview[\\[7\\]](#cite-id-3nz4vlfc4tr)\n\nThe [Wrapped Tokens](https://iq.wiki/wiki/wrapped-tokens) [whitepaper](https://iq.wiki/wiki/white-paper), dated January 24, 2019, names Republic Protocol alongside [Kyber Network](https://iq.wiki/wiki/kyber-network) and [BitGo](https://iq.wiki/wiki/bitgo) and proposes a framework for WBTC, a bitcoin-backed [ERC-20](https://iq.wiki/wiki/erc-20) token. The paper names Kyber and Republic Protocol as initial WBTC merchants.[\\[22\\]](#cite-id-oe5mnqerra) On January 31, 2019, Wang wrote that RenEx would serve as a WBTC merchant and offer direct BTC-to-WBTC swaps through SwapperD.[\\[23\\]](#cite-id-cj0vosiyel)​\n\n> “Using Ren, [smart contracts](https://iq.wiki/wiki/smart-contract) on any blockchain can control tokens on other blockchains, allowing DEXs, DeFi, and dApps to [leverage](https://iq.wiki/wiki/leverage) the liquidity available anywhere and everywhere.”[\\[24\\]](#cite-id-v46cfbk102)\n\nIn February 2021, the Ren development team joined [Alameda Research](https://iq.wiki/wiki/alameda-research). [\\[9\\]](#cite-id-f21aoklcdyo)​\n\n> \"Together, with our collective experience, expertise, and communities, our two teams will be able to contribute more value to the blockchain space than alone\"\n>\n> \"As part of joining Alameda, the Ren development team will be prioritising support for [Solana](https://iq.wiki/wiki/solana) in our [Multichain](https://iq.wiki/wiki/multichain) libraries, and in [RenVM](https://iq.wiki/wiki/renvm) itself. This support is currently under audit, and we anticipate that we will be able to begin bridging assets to/from [Solana](https://iq.wiki/wiki/solana) in Q2. Doing so will have a profound impact on [Serum](https://iq.wiki/wiki/serum), but also on the wider Solana ecosystem.\" - the press release stated.[\\[9\\]](#cite-id-f21aoklcdyo)\n\nWith the announcement, Loong Wang and [Taiyang Zhang](https://iq.wiki/wiki/taiyang-zhang) moved to advisory roles to guide the next phase of the [Ren Protocol](https://iq.wiki/wiki/ren-protocol).[\\[10\\]](#cite-id-00rgf0pl5nzpi)​\n\nAfter Alameda and FTX’s November 2022 bankruptcy proceedings cut off Ren development funding, the Ren team announced on November 18, 2022 that Ren 1.0 would be sunset. The plan initially disabled minting while keeping burns available during the transition. The team planned Ren 2.0, which required additional funding and development.[\\[15\\]](#cite-id-d3jp40suzt)​\n\nA community-established Ren [Foundation](https://iq.wiki/wiki/foundation) was incorporated on April 13, 2023 to support protocol research, development, and the ecosystem. Its immediate focus was Ren v2.[\\[16\\]](#cite-id-bocp8ygjcw)​\n\n[YOUTUBE@VID](XyByVQk5a90)\n\n### Talo Labs\n\nIn 2021, Wang co-founded and served as the CEO of Talo Labs, which was initially known as Talo Systems, it underwent subsequent name changes to Lasker and eventually transitioned to Talo Labs.[\\[2\\]](#cite-id-zcl1p2yr3h8) Talo Labs researches and builds therapeutics companies, platforms, and in-silico technologies. It supports talented students, from computer science backgrounds, to solve biomedical problems.[\\[3\\]](#cite-id-5f3zjm5va78)​\n\nAutomera raised $16 million in a Series A round in September 2023, co-led by Accelerator Life Science Partners and ClavystBio. Wang’s profile lists him as Automera’s founder and a board member.[\\[4\\]](#cite-id-we9bafka3gj)​[\\[1\\]](#cite-id-2em9wbmpceh)​\n\n### QDX\n\nWang co-founded QDX in 2023. His profile lists him as CEO and founder from January 2023 through May 2026. QDX is a computational drug discovery platform powered by quantum mechanics. The platform provides predictions and receptor-ligand insights for drug discovery.[\\[17\\]](#cite-id-l2csfiupk3)​[\\[1\\]](#cite-id-2em9wbmpceh)​[\\[11\\]](#cite-id-qrc77m7952)​\n\n> \"From structural biology to the design of new chemical matter, our quantum-first drug discovery platform brings the cutting edge of computational chemistry to your team.\" - QDX website expands[\\[11\\]](#cite-id-qrc77m7952)\n\nQDX’s Rush is an AI-operated virtual drug-design platform that turns research tasks into computational studies by coordinating simulation and machine-learning workflows. Walter is its conversational AI copilot for planning and launching runs and assembling reports.[\\[25\\]](#cite-id-91flncc43m) Chemspace’s virtual compound library was integrated into Rush in June 2025 and became available in the platform’s computational drug-design workflow.[\\[20\\]](#cite-id-03i986424z)​\n\nQDX’s quantum simulations mapped structural differences between mutant and wild-type JAK2 proteins and contributed structural insights to Prelude Therapeutics’ mutant-selective JAK2 V617F inhibitor program. On November 4, 2025, Prelude announced an exclusive option agreement with Incyte for that program. Prelude was to receive $35 million upfront and a $25 million equity investment, with a $100 million option exercise payment, up to $775 million in additional clinical and regulatory milestones, and royalties. Prelude retained and advanced the program during the option period.[\\[18\\]](#cite-id-kek2e43qn8)​[\\[19\\]](#cite-id-2f4us8ukju)​\n\nQDX opened academic access to its EXESS GPU-accelerated quantum-chemistry engine in February 2026, following its exascale computing work. QDX reports that EXESS powered the first double-precision exascale calculation for a scientific application and the calculation that earned the Gordon Bell Prize.[\\[21\\]](#cite-id-faanhbbalj)​[\\[17\\]](#cite-id-l2csfiupk3)​\n\n### Automera\n\nIn 2022, he also co-founded and served as the CTO at Automera, a biotechnology research company focusing on the development of Autophagy-Targeting Chimera small molecules (AUTACs).[\\[4\\]](#cite-id-we9bafka3gj)​[\\[1\\]](#cite-id-2em9wbmpceh) Wang’s current profile lists him as Automera’s founder and a board member.[\\[1\\]](#cite-id-2em9wbmpceh)​\n\n## Interviews\n\n### Loong Wang on DeFi Interoperability #01\n\nOn June 17, 2020, the Thinking Crypto YouTube channel published an interview with Loong Wang, CTO and Co-Founder of [Ren](https://iq.wiki/wiki/ren-protocol). The discussion covered [decentralized finance](https://iq.wiki/wiki/defi) (DeFi), cross-chain interoperability, [RenVM](https://iq.wiki/wiki/renvm), and the challenges of connecting different [blockchain](https://iq.wiki/wiki/blockchain) networks.\n\n[YOUTUBE@VID](vIZdp0VHe0Q)\n\nWang explained that [DeFi](https://iq.wiki/wiki/defi) enables financial activities such as lending, borrowing, and asset trading without relying on centralized intermediaries. He attributed [Ethereum's](https://iq.wiki/wiki/ethereum) position in the DeFi ecosystem to its early adoption, developer community, and application composability. However, he identified the concentration of applications and liquidity on a single network as a limitation for projects operating on other [blockchains](https://iq.wiki/wiki/blockchain).\n\nHe described [RenVM](https://iq.wiki/wiki/renvm) (Ren Virtual Machine) as a protocol designed to enable decentralized custody and cross-chain interoperability. One of its initial applications involved bringing [Bitcoin](https://iq.wiki/wiki/bitcoin) liquidity into [Ethereum](https://iq.wiki/wiki/ethereum), allowing BTC representations to be used in DeFi applications such as lending platforms and automated market makers. Wang distinguished RenVM's custody model from solutions such as [WBTC](https://iq.wiki/wiki/wrapped-bitcoin-wbtc), which relies on a centralized custodian to hold the underlying Bitcoin.\n\nWang also explained the concept of generic interoperability, which refers to enabling different [blockchains](https://iq.wiki/wiki/blockchain) to support multiple types of applications beyond simple asset transfers, including lending, trading, and automated market making. According to him, [RenVM](https://iq.wiki/wiki/renvm) was designed to coordinate interactions across multiple networks while allowing users to initiate operations through a single transaction.\n\nThe interview addressed [DeFi](https://iq.wiki/wiki/defi) vulnerabilities, particularly the March 12–13, 2020 market crash known as Black Thursday. Wang discussed how [Ethereum](https://iq.wiki/wiki/ethereum) congestion and increased [transaction fees](https://iq.wiki/wiki/transaction-fee) affected liquidation mechanisms in protocols such as [MakerDAO](https://iq.wiki/wiki/makerdao) and [Compound](https://iq.wiki/wiki/compound). He also commented on the [dForce](https://iq.wiki/wiki/dforce) hack, highlighting the tension between emergency interventions, such as freezing token transfers, and the principles of decentralization.\n\nRegarding the [blockchain](https://iq.wiki/wiki/blockchain) ecosystem, Wang discussed [Ethereum](https://iq.wiki/wiki/ethereum) 2.0 and its expected scalability improvements. He also mentioned [Polkadot](https://iq.wiki/wiki/polkadot) as a network attracting developer interest. On regulation, he suggested that restrictions in the United States could encourage projects to operate in other jurisdictions, while also increasing attention to the actual degree of decentralization within protocols.\n\nWang stated that [Ren](https://iq.wiki/wiki/ren-protocol) had initially raised approximately $35 million to develop a decentralized dark pool but later redirected its resources toward cross-chain liquidity and interoperability. At the time of the interview, the company expected [RenVM](https://iq.wiki/wiki/renvm) to launch by the end of June 2020, with plans to support additional [blockchains](https://iq.wiki/wiki/blockchain) and assets.\n\nWang considered interoperability a factor in the future adoption of [DeFi](https://iq.wiki/wiki/defi), arguing that connections between previously isolated blockchain networks could expand access to digital assets and [decentralized applications](https://iq.wiki/wiki/decentralized-application). He also discussed the possibility of transferring assets between ecosystems such as [Ethereum](https://iq.wiki/wiki/ethereum) and [Polkadot](https://iq.wiki/wiki/polkadot) without routing them back through their original networks. [\\[25\\]](#cite-id-fyi0ym6Xwlex12bl) \n\n#### RenVM Interoperability with Avalanche #02\n\nOn November 20, 2020, Loong Wang, Chief Technology Officer of [Ren](https://iq.wiki/wiki/ren-protocol) Project, delivered a presentation on the Avalanche YouTube channel addressing the proposed integration of [RenVM](https://iq.wiki/wiki/renvm) with the [Avalanche](https://iq.wiki/wiki/avalanche) network.\n\n[YOUTUBE@VID](Pl9208-Z6Cw)\n\nDuring the presentation, Wang described [RenVM](https://iq.wiki/wiki/renvm) as a protocol designed to facilitate asset transfers between separate [blockchain](https://iq.wiki/wiki/blockchain) networks without depending on centralized intermediaries. The system uses [multi-party computation](https://iq.wiki/wiki/multi-party-computation-mpc) (MPC) to distribute cryptographic operations and private key management among network participants. Through this mechanism, assets deposited on a supported blockchain can be represented by tokens on another network and subsequently redeemed for the original assets.\n\nWang discussed the limitations of existing interoperability methods, including price oracles and atomic swaps. He explained that oracles primarily provide access to external data, while atomic swaps are generally suited to direct exchanges between parties with predetermined transaction conditions. According to his assessment, these mechanisms do not cover all the requirements of more complex decentralized applications, such as lending platforms and automated market makers.\n\nThe proposed integration with [Avalanche](https://iq.wiki/wiki/avalanche) was presented as a means of making assets from other networks, including [Bitcoin](https://iq.wiki/wiki/bitcoin), [Ethereum](https://iq.wiki/wiki/ethereum), and Binance Smart Chain, available to applications operating on Avalanche. These assets could be used in different DeFi applications, including as collateral or sources of liquidity. Wang also described the interoperability model as bidirectional, allowing assets issued on Avalanche to be transferred to other supported networks.\n\nAnother subject addressed was the relationship between interoperability and [blockchain](https://iq.wiki/wiki/blockchain) [consensus mechanisms](https://iq.wiki/wiki/consensus-mechanism). Wang stated that access to external assets and users could allow developers to select networks according to their technical requirements and security models, without depending exclusively on the liquidity available within a particular ecosystem. He also discussed Avalanche's consensus architecture, which he described as technically distinct from Nakamoto and PBFT consensus models.\n\nRegarding [RenVM's](https://iq.wiki/wiki/renvm) security model, Wang explained that private key operations are distributed among multiple participants and require network agreement for authorization. He also outlined the use of economic incentives and collateral requirements intended to discourage malicious behavior among node operators.\n\nThe presentation concluded with a discussion of the planned expansion of [RenVM](https://iq.wiki/wiki/renvm) to additional [blockchain](https://iq.wiki/wiki/blockchain) networks and the availability of their supported assets within [Avalanche](https://iq.wiki/wiki/avalanche). Wang identified the development of [decentralized applications](https://iq.wiki/wiki/decentralized-application) using assets from multiple networks as one of the possible applications of this integration. 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